First-Generation vs. Second-Generation Antihistamines What are the differences between first-generation and second-generation antihistamines?, How do their pharmacokinetics influence their clinical use particularly regarding sedation and blood-brain barrier penetration? Differences Between First-Generation and Second-Generation Antihistamines How Antihistamines Work Antihistamines block histamine H1 receptors, reducing allergy symptoms like sneezing, itching, and swelling. The key difference between first-generation […]